BMI1 Polyclonal Antibody

Product Information

It targets BMI1 in WB, IP, IHC, IF, CoIP, ChIP, ELISA applications and shows reactivity with human, mouse samples.

Background Information

BMI- 1 is one of polycomb group genes, which together with Ring1 strongly enhances the E3 ubiquitin ligase activity of the Ring2 catalytic subunit. Bmi1 plays an important role in the regulation of cell proliferation and senescence through repression of the p16Ink4a and p19Arf genes and is required for maintenance of adult hematopoietic and neural stem cells. The antibody detected proteins of 45-48kda, which may include phosphorylated isoforms of the protein.

Synonyms

BMI1, PCGF4, Polycomb complex protein BMI 1, RING finger protein 51, RNF51

Full Name

BMI1 polycomb ring finger oncogene

Tested Reactivity

Human, mouse

Cited Reactivity

Human, mouse

Class

Polyclonal

Type

Antibody

Immunogen

BMI1 fusion protein

Calculated Molecular Weight

37 kDa

Observed Molecular Weight

37-43 kDa

Gene ID

648

GenBank Accession Number

BC011652

Gene Symbol

BMI1

Form

Liquid

Purification Method

Antigen affinity purification

Storage Buffer

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage Conditions

Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20°C storage.

Positive WB Detected

U-937 cells, HEK-293 cells, NCCIT cell, mouse brain tissue, K-562 cells

Positive IP Detected

U-937 cells

Positive IHC Detected

Human liver cancer tissue

Positive IF Detected

HepG2 cells

Target	BMI1
Cell Type	NSCs
Host	Rabbit
Isotype	IgG
Applications	WB, IP, IHC, IF, CoIP, ChIP, ELISA
Reactivity	Human, mouse
Conjugate	Unconjugated
Keywords	NSCs; Rabbit; IgG; WB, IP, IHC, IF, CoIP, ChIP, ELISA