CD44 Polyclonal Antibody

Product Information

It targets CD44 in WB, IP, IHC, IF, FC, CoIP, Cell treatment, ELISA applications and shows reactivity with human, mouse, rat samples.

Background Information

CD44 is a type I transmembrane glycoprotein that mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands. Adhesion with HA plays an important role in cell migration, tumor growth and progression. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. This protein exists in multiple forms (with molecular weight ranging from 16 kDa to over 200 kDa) generated by alternative RNA splicing and extensive post-translational modifications.

Synonyms

CD44, CD44 antigen, CDW44, CSPG8, ECMR III, Epican, HCELL, Heparan sulfate proteoglycan, Hermes antigen, HUTCH I, Hyaluronate receptor, IN, MC56, MDU2, MDU3, MIC4, MUTCH I, PGP 1, PGP I, Pgp1, Phagocytic glycoprotein 1, Phagocytic glycoprotein I

Full Name

CD44 molecule (Indian blood group)

Tested Reactivity

Human, mouse, rat

Cited Reactivity

Human, mouse, rat, Bovine, sika deer

Type

Antibody

Class

Polyclonal

Immunogen

CD44 fusion protein

Calculated Molecular Weight

742 aa, 82 kDa

Observed Molecular Weight

80-95 kDa

GenBank Accession Number

BC004372

Gene ID

960

Gene Symbol

CD44

Form

Liquid

Purification Method

Antigen affinity purification

Storage Buffer

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage Conditions

Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20°C storage.

Positive WB Detected

MDA-MB-231 cells, HeLa cells, HUVEC cells, mouse thymus tissue, A549 cells

Positive IP Detected

HeLa cells

Positive IHC Detected

Human lung cancer tissue, human colon cancer tissue, human oesophagus cancer tissue

Positive IF Detected

HeLa cells, human colon cancer tissue

Positive FC Detected

HeLa cells

Target	CD44
Cell Type	Types 1 and 2 astrocytes
Host	Rabbit
Isotype	IgG
Applications	WB, IP, IHC, IF, FC, CoIP, Cell treatment, ELISA
Reactivity	Human, mouse, rat, bovine, sika deer
Conjugate	Unconjugated
Keywords	Types 1 and 2 astrocytes; Rabbit; IgG; WB, IP, IHC, IF, FC, CoIP, Cell treatment, ELISA