DARPP32/PPP1R1B Polyclonal Antibody

Product Information

It targets DARPP32/PPP1R1B in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Background Information

Dopamine- and cAMP-regulated neuronal phosphoprotein (DARPP32) , also known as protein phosphatase 1 regulatory subunit 1B (PPP1R1B), is a substrate of cAMP-dependent protein kinase (PKA) enriched in dopamine-innervated brain areas. Overexpression of DARPP32 has been shown to block gastric tumor cell apoptosis (PMID: 21741919). DARPP32 also drives lung tumor growth through a similar ERBB3-mediated resistance mechanism (PMID: 34675407). The molecular weight of DARPP32 is about 32 kDa.

Synonyms

DARPP 32, DARPP32, PPP1R1B

Full Name

Protein phosphatase 1, regulatory (inhibitor) subunit 1B

Tested Reactivity

Human, mouse, rat

Type

Antibody

Class

Polyclonal

Immunogen

DARPP32/PPP1R1B fusion protein

Calculated Molecular Weight

23 kDa

Observed Molecular Weight

32 kDa

GenBank Accession Number

BC001519

Gene ID

84152

Gene Symbol

PPP1R1B

Form

Liquid

Purification Method

Antigen affinity purification

Storage Buffer

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage Conditions

Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20°C storage.

Positive WB Detected

Mouse brain tissue, HeLa cells, HEK-293 cells, human brain tissue, rat brain tissue

Positive IHC Detected

Mouse brain tissue, rat brain tissue

Positive IF Detected

Mouse brain tissue

Target	DARPP32
Cell Type	GABAergic neurons
Host	Rabbit
Isotype	IgG
Applications	WB, IHC, IF, ELISA
Reactivity	Human, mouse, rat
Conjugate	Unconjugated
Keywords	GABAergic neurons; Rabbit; IgG; WB, IHC, IF, ELISA