FRZB Monoclonal Antibody
CAT#: NSC-P007
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Overview
Specification
Target
|
FRZB |
Cell Type
|
NSCs |
Host
|
Mouse |
Isotype
|
IgG1 |
Applications
|
WB, ELISA |
Reactivity
|
Human, mouse |
Conjugate
|
Unconjugated |
Keywords
|
NSCs; Mouse; IgG1; WB, ELISA |
Product Information
|
It targets FRZB in WB, ELISA applications and shows reactivity with Human, mouse samples. |
Background Information
|
Frzb (also known as sFRP3) is a member of the secreted frizzled related protein (SFRP) family, originally identified as a chondrogenic factor during bone morphogenesis (PMID: 29209231). It was subsequently shown to be a regulator in Wnt signaling, and also have a role in regulating cell growth and differentiation in specific cell types. FRZB was seen to be acting as an oncogene in some cancer, such as metastatic renal cancer. |
Synonyms
|
FIZ, FRE, Frezzled, FRITZ, frizzled related protein, Frizzled related protein 1, FRP, FRP 3, FRZB, FRZB 1, FRZB PEN, FRZB1, FZRB, hFIZ, sFRP 3, SFRP3, SRFP3 |
Full Name
|
Frizzled-related protein |
Tested Reactivity
|
Human, mouse |
Cited Reactivity
|
Human |
Class
|
Monoclonal |
Type
|
Antibody |
Immunogen
|
FRZB fusion protein |
Calculated Molecular Weight
|
325 aa, 36 kDa |
Observed Molecular Weight
|
36 kDa |
Gene ID
|
2487 |
GenBank Accession Number
|
BC027855 |
Gene Symbol
|
FRZB |
Form
|
Liquid |
Purification Method
|
Protein G purification |
Storage Buffer
|
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions
|
Store at -20°C. Aliquoting is unnecessary for -20°C storage. |
Positive WB Detected
|
LNCaP cells, 4T1 cells, MKN-45 cells, SGC-7901 cells |
All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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