PAX6 Monoclonal Antibody

Product Information

It targets PAX6 in WB, IHC, IF, ELISA applications and shows reactivity with Human, mouse, rat samples.

Background Information

PAX6, a paired domain and homeodomain-containing transcription factor. Interaction with TRIM11 leads to ubiquitination of PAX6 and its proteasomal degradation. PAX6 is one of the earliest genes expressed in the eye field and considered a master control gene for retinal and eye development. PAX6 also regulates the development of the olfactory, central nervous systems, pituitary, and pancreas. PAX6 mutations can cause complex ocular disorders such as aniridia and Peter's anomaly.

Synonyms

AN, AN2, Aniridia type II protein, D11S812E, MGDA, Oculorhombin, paired box 6, Paired box protein Pax 6, PAX6, WAGR

Full Name

Paired box 6

Tested Reactivity

Human, mouse, rat

Type

Antibody

Class

Monoclonal

Immunogen

PAX6 fusion protein

Calculated Molecular Weight

47 kDa

Observed Molecular Weight

47 kDa

GenBank Accession Number

BC011953

Gene ID

5080

Gene Symbol

PAX6

Form

Liquid

Purification Method

Protein A purification

Storage Buffer

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Storage Conditions

Store at -20°C. Aliquoting is unnecessary for -20°C storage.

Positive WB Detected

Rat retina tissue, JAR cells, hTERT-RPE1 cells, HeLa cells, K-562 cells, Neuro-2a cells

Positive IHC Detected

Mouse eye tissue, mouse brain tissue, rat brain tissue

Target	PAX6
Cell Type	Dopaminergic neurons
Host	Mouse
Isotype	IgG1
Applications	WB, IHC, IF, ELISA
Reactivity	Human, mouse, rat
Conjugate	Unconjugated
Keywords	Dopaminergic neurons; Mouse; IgG1; WB, IHC, IF, ELISA