Recombinant human NeuN protein, GST & His

Species	Human
Tag	GST & His
Expression Systems	E.coli
Keywords	Neural recombinant proteins

Synonyms	RFOX3_HUMAN; RNA binding protein fox-1 homolog 3; RBFOX3; Fox-1 homolog C; Neuronal nuclei antigen (NeuN antigen); FOX3; NEUN; FOX-3; HRNBP3
Description	This gene encodes a member of the RNA-binding FOX protein family which is involved in the regulation of alternative splicing of pre-mRNA. The protein has an N-terminal proline-rich region, an RNA recognition motif (RRM) domain, and a C-terminal alanine-rich region. This gene produces the neuronal nuclei (NeuN) antigen that has been widely used as a marker for post-mitotic neurons. This gene has its highest expression in the central nervous system and plays a prominent role in neural tissue development and regulation of adult brain function. Mutations in this gene have been associated with numerous neurological disorders. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Trait	Liquid
Gene ID	146713
SWISS	A6NFN3
Theoretical Molecular Weight	38 kDa
Detection Molecular Weight	47 kDa
Endotoxin	Not analyzed
Purity	>95% as determined by SDS-PAGE
Purification Method	AC
Concentration	＞0.5 mg/ml
Activity	Not tested
Buffer	20 mM Tris-HCl (pH=8.0)
Storage	Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
Notes	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.