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Carbidopa

Carbidopa

Catalog No.: PC0037

Size: 5 mg,10 mg, 50 mg, 100 mg, 200 mg

Description

Carbidopa ((S)-(-)-Carbidopa), a peripheral decarboxylase inhibitor, can be used for the research of Parkinson's disease. Carbidopa is a selective aryl hydrocarbon receptor (AhR) modulator. Carbidopa inhibits pancreatic cancer cell and tumor growth.

Molecular Weight 226.23
Formula C10H14N2O4
CAS No. 28860-95-9
Appearance Solid
Color White to off-white
SMILES OC1=C(O)C=CC(CC(NN)(C(O)=O)C)=C1
Shipping Room temperature in continental US; may vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
In Vitro Carbidopa ((S)-(-)-Carbidopa) exhibits activities similar to that described for other AhR ligands in BχPC3 and Capan-2 cells, namely the induction of CYP1A1 and CYP1A2, which are inhibited by AhR antagonists such as CH223191.
In Vivo Carbidopa also induces nuclear uptake of the AhR, and in vivo studies show that carbidopa at a dose of 1 mg/mouse significantly inhibits tumor growth in athymic nude mice bearing BχPC3 cells as xenografts.
All of our services are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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