EAD1

Catalog No.: PC0024

Size: 50 mg, 100mg, 250mg

EAD1 is a potent autophagy inhibitor with antiproliferative activity in lung and pancreatic cancer cells. EAD1 also induces apoptosis.

Molecular Weight	484.42
Formula	C24H27Cl2N7
CAS No.	1644388-26-0
SMILES	CN(CCNCC1=CN(CC2=CC=C(Cl)C=C2)N=N1)CCNC3=CC=NC4=CC(Cl)=CC=C34
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
*In Vitro*	EAD1 (0-200 μM; 72 hours) has antiproliferative activity against human cancer cell lines. EAD1 (5-75 μM; 24 hours) induces apoptosis in the H460 cells in a concentration-dependent manner. EAD1 (1-25 μM; 24 hour) increases the punctate LC3 signal in H460 cells.

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