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Glychionide A

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Glychionide A

Glychionide A

Catalog No.: PC0031

Size: 1 mg,5 mg, 10 mg,50 mg

Description

Glychionide A is a flavonoside that can be found in the roots of Glychirriza glabra. Glychionide A promotes apoptosis and autophagy of PANC-1 pancreatic cancer cells. Glychionide A can be used for the research of cancer.

Molecular Weight 446.36
Formula C21H18O11
CAS No. 119152-50-0
Appearance Solid
SMILES O=C1C(C(OC(C2=CC=CC=C2)=C1)=C3O)=C(C=C3O[C@@H]([C@@H]([C@H]4O)O)O[C@@H]([C@H]4O)C(O)=O)O
Shipping Room temperature in continental US; may vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
In Vitro Glychionide A (3.12-100 μM) significantly inhibits the proliferation of the PANC-1 pancreatic cancer cells, with an IC50 of 14 μM.
Glychionide A (7-28 μM) induces both autophagy and apoptosis in pancreatic cancer cells.
Glychionide A (7-28 μM) causes G2/M arrest of PANC-1 pancreatic cancer cells.
Glychionide A (7-28 μM) causes generation of ROS in PANC-1 cells.
All of our services are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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