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Spiclomazine

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Spiclomazine

Spiclomazine

Catalog No.: PC0034

Size: 5 mg,10 mg, 25 mg,50 mg, 100 mg, 200 mg, 500 mg

Description

Spiclomazine (Clospirazine) is a potent mutant KRAS(G12C) inhibitor that selectively inhibits mutant KRAS-driven pancreatic cancer. Spiclomazine can eliminate KRas-GTP levels in KRAS-driven pancreatic cancer and effectively inhibit RAS-mediated signaling. Spiclomazine significantly inhibits tumor progression in mouse renal capsule xenotransplantation models.

Molecular Weight 446.03
Formula C22H24ClN3OS2
CAS No. 24527-27-3
Appearance Solid
Color White to off-white
SMILES O=C1CSC2(CCN(CCCN3C4=C(C=CC=C4)SC5=CC=C(Cl)C=C35)CC2)N1
Shipping Room temperature in continental US; may vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
All of our services are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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