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DSL6A/C1

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DSL6A/C1

Catalog No.: PC0008

Description

DSL6A/C1 is derived from transplantable acinar cell carcinoma (DSL-6) established from primary pancreatic cancer in diazaserine-treated Lewis rats. Expression of the ductal cell marker OC.2 is shown along with subpopulations expressing the ductal markers OV-6, CK-7, and CK-19. DSL6A/C1 cells have been reported to be tumorigenic in Lewis rats and produce solid tumors composed of duct-like structures surrounded by dense fibrous tissue. This cell line lost structural and immunohistochemical acinar cell markers during culture and retransplantation, while acquiring ductal cell markers.

Origin Rat pancreatic carcinoma
Application Study of pancreatic carcinomas, differentiation of acinar/ductal cells.
Biological Source Rat pancreas
Growth Mode Adherent
Karyotype Not specified
Morphology Polygonal
Products Expresses CFTR protein
Receptors Lacks CCK-A receptors
Technique Cell culture, suitable for mammals.
Relevant Disease Cancer
Shipped In Dry ice
Culture Medium Waymouth′s MB 752/1 + 2mM Glutamine + 10% Foetal Bovine Serum (FBS) (Heat Inactivated).
All of our services are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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