Early diagnosis of pancreatic cancer, whether at initial diagnosis or postoperative recurrence, as well as accurate prediction of prognosis in the context of biomarker discovery is a huge challenge. Recent innovations in high-throughput technologies have made it possible to discover specific biomarkers of cancer using genomics, transcriptomics, proteomics, metabolomics, and more. The occurrence and regulation of life phenomena are extremely complex. During the occurrence and development of complex diseases such as tumors, autoimmune diseases, and metabolic diseases, changes and regulation at multiple levels such as transcriptome, proteome, and epigenetics are involved.
Fig. 1. A conceptual review of pancreatic cancer biomarkers from a variety of "omics" levels. (Turanli B, et al., 2021)
Services We Offer
Alfa Cytology can provide you with multi-omics analysis services for pancreatic cancer, integrating information at different levels such as mRNA, regulatory factors, proteins, metabolism, etc., to build a gene regulatory network.
| Services | Description |
|---|---|
| Pancreatic Cancer Transcriptomics Research Service | Transcriptome sequencing is a comprehensive and rapid acquisition of almost all transcript sequence information of a specific tissue or organ of a species in a certain state through high-throughput sequencing technology. Explore the interactions between RNAs, build potential RNA regulatory networks, and systematically reveal the transcriptional regulatory laws of the RNA world behind biological phenomena. |
| Pancreatic Cancer Proteomics Research Service | Proteomics uses high-throughput detection methods to study protein expression levels, post-translational modifications, protein-protein interactions, etc. The study of proteome not only helps to better understand the laws of life activities, but also provides theoretical basis for elucidating the mechanism of pancreatic cancer. |
| Pancreatic Cancer Metabolomics Research Services | Metabolomics is the study of changes in metabolic products of cells, tissues or organisms after they are stimulated or perturbed. It is used to analyze the relationship between metabolites and physiological and pathological changes in the body, and to reveal the nature of the body's life metabolic activities. |
| Pancreatic Cancer Epigenetic Research Services | Epigenomics studies epigenetic modifications at the genome level and studies modification information of non-DNA sequence changes. It plays an important role in the transformation of pancreatic cancer and can provide potentially effective targets for the diagnosis and treatment of pancreatic cancer. |
| Pancreatic Cancer Spatial Omics Research Service | Spatiomics mainly studies the relative positions of cells in tissue samples to reveal the impact of cell spatial distribution on diseases. It has important reference significance for in-depth understanding of the biological mechanisms of the occurrence and progression of PDAC and the development of clinically relevant biomarkers for early diagnosis. |
Alfa Cytology is committed to providing customers with one-stop basic research services on pancreatic cancer. If you are interested in our pancreatic cancer omic analysis service, please contact us for more details.
Reference
- Turanli B, et al. Current State of "Omics" Biomarkers in Pancreatic Cancer. J Pers Med. 2021 Feb 14;11(2):127.