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RIN-5F

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RIN-5F

Catalog No.: PC0018

Description

RIN-5F is a secondary clone of the rat islet tumor cell line RIN-m (Sigma catalog number 95071701). Cloning was performed by limiting dilution in RPMI 1640, 10% FBS, and 20% conditioned medium. Conditioned medium contains growth hormone and prolactin produced by rat pituitary tumor cells GH3. RIN-5F cells secrete insulin, produce high levels of the key APUD enzyme, and contain membrane-bound secretory granules.

Origin Rat islet cell tumour
Application Study of pancreatic islet cell biology eg. synthesis, storage and secretion of insulin
Biological Source Rat pancreas
Growth Mode Adherent
Karyotype Not specified
Morphology Not specified
Products Insulin
Receptors Not specified
Technique Cell culture, suitable for mammals.
Relevant Disease Cancer
Shipped In Dry ice
Culture Medium RPMI 1640 + 2mM Glutamine + 10% Foetal Bovine Serum (FBS).
All of our services are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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