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TGP 49

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TGP 49

Catalog No.: PC0007

Description

TGP 49 has been isolated from acinar cell carcinomas arising in the pancreas of transgenic Tg(E1a-1-SV40E)Bri18 mice. These mice carry a pseudogene construct consisting of a pancreatic-specific elastase 1 promoter linked to the SV40T antigen, thereby representing an animal model of pancreatic carcinogenesis. TGP 49 secretes small amounts of somatostatin and is one of a series of cell lines isolated from pancreatic tumors deposited at ECACC. They are reported not to secrete amylase or lipase but do secrete trypsin.

Origin Mouse pancreatic acinar carcinoma
Application Study of endocrine pancreas carcinomas, hormone assays.
Biological Source Mouse pancreas
Growth Mode Adherent
Karyotype Not specified
Morphology Trabecular
Products Somatostatin (low levels)
Receptors Not specified
Technique Cell culture, suitable for mammals.
Relevant Disease Cancer
Shipped In Dry ice
Culture Medium DMEM:Ham′s F12 (1:1) + 2mM Glutamine + 10% Foetal Bovine Serum (FBS) (Heat Inactivated).
All of our services are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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