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TGP 52

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TGP 52

Catalog No.: PC0014

Description

TGP 52 has been isolated from islet tumors arising in the pancreas of transgenic Tg (E1a-1-SV40E) Bri18 mice. These mice carry a pseudogene construct consisting of a pancreatic-specific elastase 1 promoter linked to the SV40T antigen, thereby representing an animal model of pancreatic carcinogenesis. TGP 52 cells are SV40T antigen positive and secrete somatostatin and are one of a series of pancreatic tumor lines deposited at ECACC. The cells briefly produce insulin in culture and then somatostatin.

Origin Mouse islet cell tumour
Application Study of endocrine pancreas carcinomas, hormone assays.
Biological Source Mouse pancreas
Growth Mode Adherent
Karyotype Not specified
Morphology Trabecular
Products Somatostatin
Receptors Not specified
Technique Cell culture, suitable for mammals.
Relevant Disease Cancer
Shipped In Dry ice
Culture Medium DMEM:Ham′s F12 (1:1) + 2mM Glutamine + 10% Foetal Bovine Serum (FBS) (Heat Inactivated).
All of our services are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

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