Nucleic Acid-based Cancer Vaccine Development Services
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Nucleic Acid-based Cancer Vaccine Development Services

A cancer vaccine is a medication that stimulates the body's immune response by increasing T-cell responses or antibody production, so successfully preventing or inhibiting the development of cancer. Nucleic acid-based cancer vaccines exert their effects by delivering gene instructions encoding tumor antigens to host cells. Alfa Cytology will be able to provide you with specialized Nucleic Acid-based Cancer Vaccine Development Services.

Introduction to Nucleic Cancer Vaccines

Nucleic acid vaccines can be divided into DNA vaccines and RNA vaccines. Nucleic acid vaccines, also referred to as gene vaccines, are a novel vaccine technology. They function by transporting gene sequences for specific pathogen proteins in plasmid vectors and injecting them into the human body. Once inside the body's cells, these genes are transcribed and translated by the cells using their mechanisms to produce antigenic proteins of the pathogen. These antigenic proteins stimulate the immune system to produce an immune response against the pathogen, achieving the goal of preventing or treating the disease. Nucleic acid vaccines are considered a promising vaccine technology due to their simple preparation and rapid design and production capabilities.

Fig.1 Mechanism of cancer vaccines.Fig.1 Mechanism of cancer vaccines. (Liu, J., et al., 2022)

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DNA cancer vaccines are considered more stable than RNA vaccines because RNA, structurally different from DNA, suffers from widespread RNA enzyme distribution. On the other hand, DNA cancer vaccines must first reach the cell nucleus to be effective. mRNA, a type of RNA, can directly translate and express antigens within the cell cytoplasm. Alfa Cytology is dedicated to delivering two tailored nucleic acid cancer vaccines with confidence.

RNA Cancer Vaccine

The RNA cancer vaccine comprises RNA sequences administered via injection to initiate an immune response, enabling the body to combat cancer cells effectively.

  • Lower stability
  • No risk of insertional mutagenesis
  • Efficient production of antigens
  • Lower production of antigens

DNA Cancer Vaccine

The DNA cancer vaccine uses specific DNA sequences containing antigens unique to cancer cells to stimulate the immune system and target cancer cells.

  • Higher stability
  • Little risk of insertional mutagenesis
  • Slower antigen production
  • Higher production of antigens

With the advancement of basic research and the non-accumulation of research data, nucleic acid vaccines have been in an important research position as a newcomer to cancer vaccines. Thanks to important advances in delivery systems, the development of nucleic acid cancer vaccines has been greatly advanced. Alfa Cytology specializes in providing services for the development of cancer vaccines, including customized services for the development of nucleic acid cancer vaccines.

Why Choose Us?

Professional and well-trained core technical team.

Professional and well-trained technical team.

Advanced experimental equipment.

Advanced experimental equipment.

Empowering success through cooperation.

Empowering success through cooperation.

Strict quality control system.

Strict quality control system.

 Alfa Cytology's team of experts has a deep understanding of nucleic acid cancer vaccine science and extensive experience in assay development and validation to ensure efficient and high-yield production of your nucleic acid cancer vaccine. You can rely on us to deliver a safe and effective vaccine that meets all regulatory requirements. Contact us to learn more about how we can meet the unique needs of each of your projects and advance your research with confidence.

Reference

  1. Liu, J., et al.; (2022). Cancer vaccines as promising immuno-therapeutics: platforms and current progress. Journal of hematology & oncology, 15(1), 28. https://doi.org/10.1186/s13045-022-01247-x
 For Research Only.