Chemokine Analysis Services for Brain Tumors

Chemokine receptors and their ligands are widely involved in various pathophysiological processes such as cell growth, differentiation, apoptosis, tissue damage, tumor growth, and metastasis in the body. Chemotaxis, activation of immune cells, or inhibition of vascular proliferation will play an anti-brain tumor role. Stimulating tumor growth, chemotactic tumor cells, promoting vascular proliferation, and promoting extracellular matrix degradation will promote brain tumor growth infiltration and invasion, and metastasis. Thus, chemokines play an important and bidirectional role in the development of brain tumors.

We provide chemokine analysis services for brain tumors

Chemokines have been shown to influence the level of immune cell infiltration and immune response in the tumor microenvironment, thereby regulating brain tumorigenesis and progression, such as CXC, etc. Alfa Cytology can provide brain tumor-related chemokine analysis services to our clients. We can analyze and quantify chemokines by single and multiplexed assays. We are also equipped with a high throughput flow cytometer that allows CBA immunoassays to achieve multiplex results from a single small number of samples, and this approach avoids the artifacts associated with enzyme-dependent signal generation in traditional enzyme-linked immunosorbent assays (ELISA).

Technical advantages

• Chemokine assays can be performed in single and multiplexed formats with high sensitivity, wide dynamic range, and convenience.
• It is suitable for a wide range of sample matrices such as cell cultures, serum, plasma, and cerebrospinal fluid.
• It requires a small sample volume for the simultaneous detection of multiple analytes, which greatly improves throughput and enables new analytical methods compared to traditional methods.

The complex interactions between chemokine receptors and their ligands require an in-depth understanding of brain tumor microenvironment biology and better predictive clinical models to introduce a new generation of chemokine-based immuno-oncology therapeutic strategies, and Alfa Cytology can help you do just that. Please feel free to contact us to discuss any project related to chemokines in brain tumors.