Sequencing Services for Brain Tumors

The ability of WGS to provide a comprehensive view of the entire genome and our ability to handle large sample data make WGS a powerful tool for basic brain tumor research. We can provide WGS services to the brain tumor research field to help our clients gain more information about brain tumor disease.

Mutations in whole exome regions are most likely to affect the development of brain tumors. We provide a reliable method for brain tumor genomic research by accurately detecting SNV and InDel through WES, which can efficiently resolve cancer susceptibility and pathogenicity genes. Our WES service helps researchers to find meaningful biomarkers indicating efficacy and has become the method of choice for comparing brain tumors with normal samples.

Targeted sequencing focuses only on genes of interest. We can accurately detect mutations in brain tumor samples with targeted sequencing technology. Whether you focus on a few genes or hundreds of genes, we offer targeted sequencing with greater sensitivity and specificity, higher coverage, and high-quality data. It helps you to research key genes and important variants associated with tumor development and individualized drug use.

We offer single-cell sequencing technology that allows you to take a new perspective on brain tumor and neuroscience problems and can help you discover genomic variants in brain tumor cells. It will help you to deepen your understanding of the cellular state, the nature of transcription and regulation of gene expression, and even the pathological process of brain tumors.

We provide customers with methylation sequencing services to obtain not only methylation information of brain tumors but also copy number variants. We also support co-application with other standard techniques such as histology, making DNA methylation analysis an effective adjunct to brain tumor classification, especially for poorly characterized and rare brain tumor types and subtypes.

We offer snRNA-seq service to extract nuclei from tissues and then perform high-throughput sequencing analysis of the transcriptome at the level of individual nuclei. By examining the gene expression status of individual nuclei, we can help you uncover the heterogeneity among brain tumor cells. We have also developed a raw letter process specifically for snRNA-seq data analysis.

We offer nanopore sequencing services for the complete characterization of structural variants, repeat regions, single nucleotide variants, haplotype fixation, RNA splice variants, fusion transcripts, and epigenetic modifications. We master the size and surface properties of nanopores and applied voltages and solution conditions to detect different types of biomolecules.