Multi Omics Analysis Services for Brain Tumors

To better utilize the phenomenon of up-/down-regulation of gene expression for brain tumor detection and diagnosis, we offer brain tumor-specific gene analysis services to our clients. This includes gene expression analysis, target gene transcription factor analysis, single-cell sequencing analysis, protein interaction network analysis, genetic linkage and localization analysis, single nucleotide polymorphism (SNP) typing, and methylation site detection.

We offer brain tumor genomic analysis services to our clients to identify DNA alterations that drive tumor growth and discover genetic changes in specific genes. We use high-throughput whole genome sequencing and next-generation microarray capture sequencing methods that allow an analysis of copy number changes and base modifications in many previously characterized brain tumor samples.

We utilize spatial transcriptome technology to efficiently detect gene expression patterns in brain tumor tissues at spatially primitive locations. We can detect total mRNA from intact brain tumor tissue sections, combine the spatial information of total mRNA with morphological content, and map the locations where all gene expression occurs to obtain a complete gene expression atlas.

We provide metabolomics analysis services for brain tumors to our clients. We apply techniques such as nuclear magnetic resonance and mass spectrometry to detect metabolite changes in various brain tumor tissues to help you study various metabolite molecules and their functions.

We apply a variety of technologies to provide our clients with spatial proteomics and protein microarray services for brain tumors. This allows us to compare brain tumor stem cells (BTSC) with neural stem cells, search for BTSC-specific markers, explore the mechanisms of BTSC differentiation, and provide new ideas for the origin, diagnosis, and treatment of brain tumors.

We use gene microarray technology and bioinformatics analysis to screen for core genes (differentially expressed genes) and signaling pathways associated with brain tumors, including glioblastoma multiforme. We can also perform clustering analysis and functional enrichment analysis of differential genes while constructing protein-protein interactions (PPI) networks to screen core genes. Finally, we validate the expression levels of the core genes with database and genome-wide expression profile data.

We provide epigenetic analysis services for brain tumor samples, structural alteration and single base mutation analysis services, rare gene mutation detection services, and intratumor genetic heterogeneity analysis services to our clients. We can also assess the relative risk of brain tumor development by combining existing mutations with the relationship between the genes and brain tumorigenesis.

We provide our clients with brain tumor imaging omics analysis services that can extract high-throughput quantitative features from medical images reflecting the heterogeneity of brain tumors. We convert them into high-dimensional data that can subsequently be mined to discover their correlation with tumor histological features reflecting underlying genetic mutations and brain tumors.