Custom Electrochemical Biosensor Prototyping from Concept to Functional Device Services

Custom Electrochemical Biosensor Development

Our biosensor design and fabrication service provides a complete pipeline from target specification to functional prototype delivery. We work with diagnostic startups, medical device companies, and academic groups to develop sensitive, label-free electrochemical detection platforms for biomarkers such as cancer antigens, cardiac markers, and infectious disease targets. Using screen-printed electrodes as the transducer substrate, we engineer surface chemistries optimized for high-specificity bioreceptor immobilization, including antibodies, aptamers, or enzymes. Our interdisciplinary team handles electrode layout, material selection, microfabrication, and iterative optimization of electrochemical parameters (cyclic voltammetry, differential pulse voltammetry, electrochemical impedance spectroscopy) to achieve the required sensitivity, selectivity, and stability. The final deliverable is a fully characterized sensor prototype with a detailed performance report, enabling seamless transition to point-of-care or wearable integration.

Service scope is defined collaboratively at project initiation, covering detection modality (amperometric, potentiometric, impedimetric), electrode format (single-use screen-printed, microelectrode array), and target analyte. We provide comprehensive documentation including fabrication protocols, surface chemistry details, and quality control data to support downstream validation and scale-up.

Our Biosensor Development Offering

Sensor Design & Material Selection

Select optimal electrode geometry, substrate (carbon, gold, platinum), and nanomaterial coatings based on target analyte and detection range. We provide rationale for material choices during design review.

Surface Functionalization & Bioreceptor Immobilization

Engineer reproducible surface chemistries (e.g., SAMs, polymer brushes) and immobilize antibodies, aptamers, or enzymes with controlled orientation to maximize binding capacity and signal-to-noise ratio.

Electrochemical Characterization & Prototype Delivery

Perform quantitative testing for sensitivity, limit of detection, linear range, selectivity against interferents, and batch-to-batch reproducibility. Deliver functional electrodes with performance report and fabrication guidelines.

Our Biosensor Design Workflow

1. Concept & Target Specification We collaborate with you to define the target biomarker, required detection range, sample matrix (buffer, serum, whole blood), and performance targets (LOD, assay time). Feasibility assessment guides electrode format and surface chemistry selection.

2. Electrode Design & Microfabrication Based on specifications, we design the electrode layout and fabricate screen-printed or microelectrode arrays using industry-standard materials. We incorporate nanomaterial coatings (e.g., carbon nanotubes, metal nanoparticles) to enhance electron transfer and surface area.

3. Surface Functionalization & Bioreceptor Immobilization We apply controlled surface chemistries to attach bioreceptors covalently or via affinity interactions. Optimisation of immobilization density and blocking minimizes non-specific binding and maximizes signal stability.

4. Electrochemical Characterization & Prototype Delivery We perform cyclic voltammetry, differential pulse voltammetry, and impedance spectroscopy to evaluate sensor performance. Deliverables include functional electrodes, multiplexed calibration data, and a comprehensive performance report with QC metrics.

Service Deliverables

Deliverable	Description
Custom Screen-Printed Electrodes	Batch of functional electrodes (quantity as scoped) with defined geometry, materials, and surface chemistry, ready for immediate electrochemical testing.
Functionalized Sensor with Immobilized Bioreceptor	Electrodes with optimized bioreceptor layer (antibody, aptamer, or enzyme) and blocking protocol, including validation of binding activity and stability.
Performance Report & Documentation	Detailed report covering sensitivity, LOD, linear range, selectivity, reproducibility, CV and DPV traces, surface chemistry protocols, and recommendations for downstream integration.

Why Choose Our Biosensor Service

Comprehensive Material Selection

We evaluate carbon, gold, platinum substrates, and nanomaterial coatings (e.g., graphene, MXenes, metal nanoparticles) to match your analyte and matrix. Each material choice is documented with rationale.

Custom Surface Chemistry Optimization

We design and test SAMs, polymer layers, and crosslinking strategies to maximize bioreceptor orientation and binding capacity, achieving low detection limits and minimal fouling.

Iterative Performance Tuning

Multicycle feedback: we optimize sensor parameters basing on initial electrochemical data, adjusting electrode design, surface chemistry, or measurement conditions until targets are met.

Full Documentation & Technology Transfer

You receive fabrication protocols, QC results, and performance data sufficient to reproduce sensors in your lab or support scale-up discussions with manufacturing partners.

Featured Publication

Development of a Simple Isatin-Based Electrochemical Immunosensor on a Screen-Printed Gold Electrode for Highly Sensitive Detection of Carcinoembryonic Antigen

View article

Ready to Develop Your Biosensor Prototype?

Contact our biosensor development team to discuss your target biomarker, detection requirements, and project timeline. We will provide a scoped proposal with clear deliverables and milestones—no obligation.

Start Your Project