Imaging Services for the Acidic Tumor Microenvironment

Relying on the technology platform of the tumor microenvironment center, Alfa Cytology provides a full range of acidic tumor microenvironment (TME) imaging services to help researchers successfully achieve their research goals.


Among all features of the tumor microenvironment (TME) caused by abnormal proliferation of solid tumors, extracellular acidity is an important indicator of malignancy grading. The acidic microenvironment of solid tumors plays a key role in their malignant biological behaviors such as development, invasion and metastasis. Therefore, being able to qualitatively and quantitatively measure the pH of the extracellular environment of tumors is of great significance for early diagnosis, evaluation of tumor development, and monitoring the efficacy of clinically applied anticancer drugs. Imaging assays have the potential for early tumor diagnosis, proper disease management, guiding individualized therapy, and evaluating efficacy. Non-invasive in vivo, real-time dynamic and quantitative imaging of the acidic tumor microenvironment is necessary.


Alfa Cytology investigates imaging methods to assess the spatial and temporal patterns of the acidic tumor microenvironment (TME). We integrate multiple imaging techniques, and our services include, but are not limited to:

MRI provides non-invasive in vivo, real-time dynamic and quantitative imaging of the tumor acidic microenvironment, which has the potential for early tumor diagnosis, proper disease management, guidance of individualized treatment, and evaluation of efficacy.

Alfa Cytology also offers contrast-based imaging of the tumor acidic microenvironment. Different contrast agents, including fluorescence, positron emission tomography (PET), single photon emission computed tomography (SPECT) and magnetic resonance (MR) contrast agents with pHLIP are used to target acidic TME.

Note: Our services list is constantly being updated and improved, please contact us by email for more up-to-date and relevant information.

Alfa Cytology has the technical power and imaging-related expertise to combine with existing organoid models to analyze biological questions in cancer metabolism that will rapidly advance your research.

Service process

  • Please let us know the details of your tumor and microenvironment related project through online consultation.
  • We will get back to you promptly and provide you with a comprehensive evaluation report of your project, including a feasibility assessment of the project and a detailed experimental protocol designed by our professional staff.
  • As our condition optimization is completed, the results report and other final products will be delivered to you immediately.
Imaging of the Acidic Tumor Microenvironment

Alfa Cytology is dedicated to supporting scientists in making groundbreaking scientific discoveries and developing new applications to accelerate new drug discovery and scientific diagnosis and treatment. We have established the tumor microenvironment center technology platform with high performance scientific instruments and high value solutions to ensure high quality services that enable scientists to explore the mysteries of life at the tumor microenvironment level. Please let us know your project requirements and we will provide you with a comprehensive service from solution to report. If you have any questions, please feel free to contact us.

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.


Alfa Cytology is a service provider specializing in tumor microenvironment research.

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