Single-cell Genome in TME
Relying on the tumor microenvironment center technology platform, Alfa Oncology provides single-cell genome sequencing and analysis services for TME research, helping researchers successfully achieve their research goals.
Cells in a cell population/tissue are heterogeneous and asynchronous. Single-cell genome sequencing solves the problem that the heterogeneity information of different single cells cannot be obtained from tumor tissue samples, and the sample size is too small for routine sequencing by performing genome amplification and sequencing of single cells in the tumor microenvironment (TME). It provides a new direction for scientists to study and analyze the behavior, mechanism, and relationship with the body of a single cell. It also provides guidance for early detection, diagnosis of disease, and individualized treatment of disease.
Single-cell genome sequencing in the tumor microenvironment is mainly based on a combination of high-quality whole-genome amplification and sequencing at the single-cell level to reveal cell population differences and cell evolutionary relationships. Due to the heterogeneity of tumor cells, this technology does not require culturing cells, and can most truly obtain the specific mutation source and accurate mutation frequency of monoclonal tumor cells, as well as distinguish the active processes in the process of tumor occurrence, development and evolution. and passive mutation, etc.
At Alfa Oncology, we have established a mature tumor microenvironment center technology platform, with a group of experienced tumor microenvironment research experts and mature technologies. Our global customers provide efficient single-cell genome sequencing and analysis services of tumors and microenvironments, helping you in tumor and microenvironment heterogeneity exploration, tumor progression research, and anti-tumor drug discovery.
Every step from material selection, library building and sequencing, to data analysis requires scientific and meticulous design to ensure high-quality research results.
For different projects, in addition to standard information analysis, through joint discussions with partners, we can formulate feasible personalized information analysis solutions, integrate various mainstream software, and optimize the analysis results to ensure the accuracy and innovation of the results.
Customized information analysis can be negotiated based on customer needs.
Note: Our services list is constantly being updated and improved, please contact us by email for more up-to-date and relevant information.
- Finding variation information at the single-cell level
- Investigating tissue and cell population heterogeneity at the single-cell level
- Analysis of tumor subclone evolution
Alfa Oncology is dedicated to supporting scientists in making groundbreaking scientific discoveries and developing new applications to accelerate new drug discovery and scientific diagnosis and treatment. We have established the tumor microenvironment center technology platform with high performance scientific instruments and high value solutions to ensure high quality services that enable scientists to explore the mysteries of life at the tumor microenvironment level. Please let us know your project requirements and we will provide you with a comprehensive service from solution to report. If you have any questions, please feel free to contact us.